On 27 Dec 1722 when Ephraim was 24, he first married
Prudence Stickney, daughter of
John Stickney (23 Jun 1666-13 Aug 1727) &
Mary Poor (6 Jun 1673-20 Aug 1737), in Newbury, MA.
Born on 15 Sep 1698 in Newbury, MA. Prudence died in Newbury, MA 7 Mar 1729/30.